Weigl and Castro have been deployed in central midfield and put on an impressive display in the 6-2 victory over Bayer Leverkusen over the weekend.
"We are focused, we take it step by step, and that is a great development for the team and a really good phase for us at the moment".
It did not take them long to draw level on aggregate, with Aubameyang scoring the first goal of the night after four minutes when he headed in at the back post following Pulisic's flick from a corner.
Bundesliga leading scorer Pierre -Emerick Aubameyang, who missed most of those chances and saw his spot kick saved, has since rediscovered his scoring form, nett ing twice against Leverkusen. Borussia Dortmund despite the defeat in the first match, remains with good chances to go to the next round, because the Dortmund will certainly come to the field, exclusively for the victory.
With play-maker Reus sidelined, the pressure falls on teenage winger Ousmane Dembele and Aubameyang to provide the goals, but defender Marc Bartra says patience is required.
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"Marco has been extremely consistent for the past weeks. and it is a big blow for us that he is not playing on Wednesday", Tuchel said.
The Germans must overturn a 1-0 deficit from the first leg as they seek a third quarter-final appearance in the competition in a decade but were already without talismanic attacking midfielder Marco Reus ands Mario Goetze. They are top of the league, a point ahead of rivals Porto, and through to the Portuguese Cup final.
Benfica coach Rui Vitoria has made two changes from the team which beat Fierense on Saturday in the Portuguese league.
And Aubameyang, who had never previously scored in the tournament's knockout stages, added his second of the game just two minutes later, before completing his treble five minutes from the end.