The Championship has been a highly competitive league this season, with Brighton and Newcastle the front-runners for top spot for the majority of the campaign.
Rafael Benitez's Magpies are a point behind Albion, with both teams likely to name unchanged teams.
Yet, Chris Hughton's Brighton have the best home record in the league and have lost just twice since the start of September, so getting a result at the AMEX Stadium tonight is going to be a tough ask for Benitez and his team.
"It is an important win for us".
His absence has been covered by Aleksandar Mitrovic, Ayoze Perez and Daryl Murphy, who have 11 Championship goals between them so far this season.
A trip to Huddersfield follows on Saturday, with the Terriers now third in the table and still with ambitions of gaining automatic promotion.
Horizon Zero Dawn preload now available, file size also revealed
Meanwhile in United Kingdom , eight major cities have been given the " Horizon Zero Dawn " makeover to mark the game's launch. For those who have pre-ordered " Horizon: Zero Dawn " on the PlayStation Store , you can now download ahead of its launch.
United go to Huddersfield on Saturday, followed by a journey to fifth-placed Reading on Tuesday, 7 March.
"There is no doubt it is a big game because of where we are in the division", said the 58-year-old.
Keith Andrews in the Sky Sports studios at half-time argued that in a game of this magnitude you simply can't give a penalty for something like that, and he's got a point.
Blackburn's hopes of avoiding relegation were boosted as they secured a 1-0 win over Derby County who are now winless in six league games, while Aston Villa won 2-0 at home to Bristol City.
Full-backs Gaetan Bong (knee) and Liam Rosenior (ankle) are edging closer to returns but centre-back Connor Goldson (heart) is out for the season.